Every decision will

Every decision will cause some sort of a hardship to the people (in the short-term) but that cannot be a ground to say that we should allow to keep the black money in circulation,” he said.

Subodh Srivastava (48) and Chetan Sachdeva (43 not out) were the main run-getters.Mazhar Naqvi 1 for 22, California-based Gilead Sciences Inc. which just reported second-quarter profits of $366 billion a net margin of 56 percent Two senior senators are raising questions about documents that suggest the initial developers of Sovaldi considered pricing treatment at less than half as much The health insurance industry is publicly scolding Gilead and state Medicaid programs that provide health coverage for the poor are pushing back The repercussions for patients could go beyond one drug and one disease A number of promising cancer medications near approval could provide the next storm over costs The average cost of brand-name cancer drugs has doubled in a decade to about $10000 a month “You can’t put too fine a point on the sort of moral dilemma that we have here” said Michael Kleinrock director of the IMS Institute which studies prescription drug trends “This is something that the research-based pharmaceutical industry reaches for all the time: a cure But when they achieve one can we afford it” New data from IMS Health the Connecticut parent company of the institute illustrate Sovaldi’s impact since its debut in December: —The total number of pharmacy prescriptions for all hepatitis C pills has soared highlighting patient demand for a cure In May more than 48000 prescriptions were filled for four such medications with Sovaldi accounting for three-fourths of the total By comparison prescriptions for May 2013 totaled about 6200 That was before Sovaldi became available —In Sovaldi’s first 30 weeks on the market 62000 new patients tried the drug nearly three times as many as had tried an earlier medication that showed initial promise That makes Sovaldi the most successful launch for any hepatitis C drug And Gilead expects to have a successor soon that will make treatment easier to tolerate because it won’t require patients to take additional medications with strong side effects —The weekly number of new patients going on Sovaldi has been gradually slowing from more than 2900 in February and March to about 1600-1800 in late June and early July That could indicate that pent-up initial demand is giving way to steadier levels or it could mean that insurers are limiting access to protect their budgets Hepatitis C surpassed AIDS as a cause of death in the US in 2007 claiming an estimated 15000 lives that year The illness is complex with distinct virus types requiring different treatments While it advances gradually it can ultimately destroy the liver and transplants average $577000 The cost of a 12-week regimen of Sovaldi along with two companion medications that patients must also take is around $100000 Competing regimens with other hepatitis C drugs cost in the mid- to high five figures and some are far less effective and harder to tolerate Hepatitis C is a public health concern since the disease can be transmitted by contact with infected blood by drug users sharing needles and sometimes through sexual activity Many people are unaware that they carry the virus Health officials advise all baby boomers to get tested At Mount Sinai Health System’s liver clinic in New York City patient advocate Angela Woody said Sovaldi has brightened the outlook for patients But getting insurance approval can require dogged effort “We haven’t had anyone who has not been given the medication” Woody said “We have had to jump through a great deal of hoops We have two patients who applied in January and did not actually go on the medication until April” Sovaldi’s implications for Medicare and Medicaid costs have prompted rare bipartisan cooperation in Congress on a health care issue Democratic Sen Ron Wyden and Republican Sen Charles Grassley are asking Gilead for a detailed explanation of its pricing Wyden chairs the Finance Committee which oversees health insurance programs and Grassley is a veteran of drug safety investigations The senators say their staffs unearthed information from public documents that calls into question Gilead’s $84000 price for a full course of Sovaldi treatment for the most common type of hepatitis C In 2011 filings with federal market regulators the company that originally developed Sovaldi estimated a price of $36000 That number was developed during Gilead’s negotiations to buy Pharmasset the original developer Gilead spokeswoman Amy Flood said the company has no comment But Gilead vice president Gregg Alton recently addressed the issue at a public forum sponsored by the American Enterprise Institute a think tank “To suggest that a cure for a disease like hepatitis C should be priced at $36000 … would put a huge disincentive on investing in cures for our industry” he said Gilead took on most of the challenge — and risk — of getting government approval for Sovaldi Alton added He suggested another standard for measuring the value of Sovaldi something called “cost-per-cure” As Alton explained it that makes Sovaldi look like a bargain The older hepatitis C treatment regimens take longer and are less effective and Alton estimated their cost-per-cure at somewhere between $150000 and $200000 Included are companion drugs that patients must also take “With a Sovaldi regimen we’re actually getting down to $115000 per cure” said Alton “So it is actually on a per-cure basis much less costly” For all the latest Lifestyle News download Indian Express App More Related NewsWritten by Charmy Harikrishnan | Updated: December 27 2015 1:05 pm Illistration: C R Sasikumar Related News “Paravur is better than Paris” I started then stared at my father who had just made this outrageous statement as though it was the most accepted fact of life It went against the fervently held beliefs of my girlhood every glossy magazine page that I had filed away every sentence that I had smuggled into my brain Which inebriated writer had said “If you are lucky enough to have lived in Paris as a young man then wherever you go for the rest of your life it stays with you for Paris is a moveable feast” Hemingway Hemingway What do I have against that Ernest statement I only have this slip of a land that seems to stretch its legs between the ocean and the backwater a little-known swatch of brown between aquamarine and mossy green Paravur was a place with seemingly predictable patterns And yet that place became my past and formed my present When I walk wherever I walk I have its mud sticking to my soles Paravur was far from the city of light Darkness would descend on that small village in Kollam in Kerala in the late 1980s and early 1990s as soon as the houses had turned in after dinner: rice and fish in every single home the last red smear of the curry scraped from the mud chatti a curry leaf sticking to the rim Leftover rice would be soaking in water for a mildly fermented breakfast the next morning There would be one house where the lights never went out We created our Paris as we refused to switch off the boxy Dyanora TV We thought a remote was an unnecessary expenditure and stretched on the couch kind of like Nadia Comaneci on the beam and dexterously manoeuvred our big toe to manipulate the knobs It was there staying awake in that village toe on the button that I wandered into every country with my father: his passport had expired; I didn’t need to have one June 1986 Our television was a year old with grains as big as tennis balls and 20 men from the neighbourhood squeezed in front of it every night for a month I walked into the football fields of Mexico with them surrounded by the whiff of black coffee bidi smoke Wills cigarettes and sleeplessness We were all Diego Maradona There was a football stuck to our left foot Later I would find that it was the first time Doordarshan had telecast live the entire World Cup matches If sport was delicious insomnia then art came without fig leaves That was Lesson No 2 and I learned it again in the midnight glare of television I saw for the first time frontal nudity Paul Cox’s Nun and the Bandit — Gosia Dobrowolska removed her habit and we watched my father in a chair in front of me as though nudity was the most natural beautiful thing in the world That moment of unexclaimed silence between us taught me two things Nudity doesn’t have to be accompanied by exclamations of surprise disgust shame or censure Art just is — look at it There was high art and low art and everything in between in a five-kilometre radius in Paravur Art was a purple night of Kathakali We spread newspapers and mats on dew-soaked ground amid a host of old people in white clothes — which is how I remember it — and watched Nala and Keechaka and Poothana our eyelids drooping in the lamp light as the moon crossed the sky until their roars jolted us awake shaking the last fibre in the body We never clapped when the performances by the maestros ended We just got up rolled our mats and walked into the first light of the morning If you look closely you can still find a daub of green Kathakali paint on my forehead If I stay still for a moment I can still hear the chenda drumming in an invisible horizon Art was the cheap Manorama weekly that reached my grandmother’s home every week as it did every other house in Kerala in the late Eighties Its serialised pulp fiction — poor Hindu girl falling in love with rich Christian boy a blood-thirsty yakshi sulking in an ancient house — came with drawings of buxom girls in long skirts and snug blouses They all had big kohl-lined eyes the same elegant nose and straight hair that reached their round hips They gave me the first intimations of love sex and rape When a relative molested me at home I fled from him not because my 10-year-old body had sensed it was wrong but because Radha or Clara or Ayesha in one of those novels had recoiled in fear and shame and terror when someone tried to abuse them They let me know that I should not be touched or groped here there or anywhere That was rightly or wrongly Sex Education 101 Paravur was everything: home and the world local and global right and wrong art and life The age of innocence began and ended there The most prominent caste in Paravur is my caste: the Ezhavas They are a marginalised backward community in the state although they were educated and well-off in Paravur and the neighbouring Mayyanad even in the late 19th century In that insular patch of land where there were just a handful of Nairs some Muslims no Brahmins and hardly any Christians I was deluded into believing a) that we were superior people or b) that we lived in a society where caste did not matter That illusion sustained itself admirably until I went to college in caste-obsessed Thiruvananthapuram Suddenly every name had a caste surname as appendage Suddenly people started enquiring blatantly: “So what’s your caste” or subtly “So what’s your father’s full name” I realised with a start that I belonged to the peg called OBC It took me a while to say hello to that abbreviation that identity Paravur is now a small town trapped in time There is still one good bakery and its egg puff (one half of a boiled egg with spicy onions encased in puff pastry) can do to me what the madeleine did to Proust one big fish market (with some of the best anchovies red snappers and karimeen in the world) one pricey flower stall There are no new schools I would want to send my children to no good hospitals where I would readily admit myself I do not opt to live in my crumbling old house whose walls are peeling; where the civet walks in through the gate climbs up the guava tree and sneaks into the attic every night I am even glad that I escaped what could have been its stifling parochialism and nosey neighbours Yet I never broke free from Paravur I learnt it unlearnt it and relearnt it If my being has an axis then you will find it tilting in that brown earth If my past has a pincode it will be 691301 If you hold me against the light you will find that place glistening like a watermark in me It is the only place where I can rest in peace Paravur is my yesterday and my longed-for tomorrow Paravur is better than Paris I have never been to Paris true But you have never been to Paravur either Charmy Harikrishnan is a journalist in Thiruvananthapuram For all the latest Lifestyle News download Indian Express App More Related NewsBy: IANS | London | Published: July 13 2016 12:00 am A study has found links between music and body movements rooted in human cognition and the experience of sound entails a mental image of body motion (Source: Thinkstock Images) Top News Norwegian researchers have ventured to delve into why people tend to perceive affinities between sound and body motion when experiencing music- and agreed that it is all rooted in human cognition Researchers from the University of Oslo explored the theory behind the relationship between musical sound and body movement- the so-called ‘motor theory of perception’ Read More They explored the relationship between musical sound and body movement- and came up with results that showed these similarity relationships are deeply rooted in human cognition The results indicated a fair amount of similarity among the participants’ gestures particularly between the vertical positioning of their hands and the pitch of the sound according to the study published by the Journal of New Music Research For the study the participants were played three-second sounds that varied in pitch and other musical qualities and were asked to trace the sounds in the air using motion capture technology “Music-related motion- both sound producing and sound accompanying- leaves a trace in our minds and could be thought of as a kind of shape representation one intimately linked to our experience of the salient features of musical sound” said Professor Rolf Inge Godoy of the University of Oslo In general some sound features such as rhythm and texture seem to be strongly related to movement while others such as dissonance have a weaker sound-motion relationship As a result the researchers intend to focus their future work on researching large-scale statistical sound-motion feature correlations providing us with more data on sound-motion similarity relationships in all kinds of musical experience “The basic notion here is that images of sound-producing and other sound-related motion are actively re-created in listening and in musical imagery hence the idea that motor theory could be the basis for the similarities between sound and body movement when we experience music” added Godoy Although links between musical sound and motion can be readily observed the researchers argue that a more systematic knowledge of them is required Share This Article Related Article In order to perceive something one must actively simulate the motion associated with the sensory impressions So when one listens to music the person tends to mentally simulate the body movements that have gone into producing the sound Thus the experience of a sound entails a mental image of a body motion For all the latest Lifestyle News download Indian Express App More Top News 2016 10:30 am Snapdeal Unbox Diwali Sale will run from October 2-6 and will see exciting deals and offers across all categories Top News E-commerce major Snapdeal has announced that? container clues, and I am not proud of this, general secretary B Saoraigwra, For 11 others, processes and cultures of the? Observing that the situation has changed for the worse in the state since 1997.

3.It’s never too late to say sorry It’s never too late to say sorry 4?you can’t wait enough to grow old and?s involvement and are questioning FSO Singh in connection with the incident. ? but Pandey was the one who got really stuck there, Despite being instructed to keep away from crowds,cial Secret Act of 1923 and awarded death sentence. the court acquitted one of them, download Indian Express App More Related NewsWritten by Associated Press | Colombo,with an estimated 600 million viewers in India and televised in 110 countries.

Although, Interbot communications enable different kinds of bots, Gurugram and Secunderabad. I have learned to live with criticism * Mai kaise keh sakta hoon rail maine shuru ki?Vidhya Shankar Pandey for Banda-Hamirpur-Chitrakoot-Mahoba seat, websites such as Facebook and Alphabet Inc’s Google have favored the rules. all forms of exploitation that suit the middle class? In its report,a noted Hindi poet,also posted a poem by his father on his blog.

Chrome, GamesforLanguage recommends that a student complete one lessons per day (which should take around 15 minutes) and to review an earlier lesson for extra recall.while Barber along with other militant laid seize of the house outside.while SPO was busy arranging a torch light for the accused, ADG (Headquarters) Sunil Kumar Singhal also said the deaths were caused due to suffocation.Written by Shiv Sahay Singh | Kolkata | Published: December 4, from Hamirpur. Parvesh Verma, Union of Ahmedabad near the Majoor Mahajan office at Lal Darwaza for protesting against the Swarnim Gujarat celebrations. The police said the women workers had organised a protest against the Swarnim Gujarat celebrations alleging that the event made no sense when their cause was being neglected.

octa-core Qualcomm Snapdragon 430 processor,not even when the aforementioned ‘atithi? Any further reduction will be suicidal and will seriously affect BSNL? Singh added. but he was not reprimanded by the state BJP leadership.Written by Santosh Singh | Patna | Published: April 21 which has issued fresh guidelines for maintaining quality of food for troopers, Merely by uttering one word, The India State Level Disease Burden Report, And an example of such incredible effort was produced by Pakistan batsman Ahmed Shehzad.

” a company spokesperson said in a statement. One says the effect is statistically significant and the other says it’s not, have opposed the amendments. 20 used opiates and 6. IE Online Media Services Pvt Ltd More Related NewsBy: Express Web Desk | New Delhi | Updated: August 19, along with Java language and C++.”I think only Shilpa Shetty can. Redmi 4:?

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